Wednesday, December 18, 2019

Ethical Dilemma On Randomized Clinical Trials - 1300 Words

Ethical Dilemma on Randomized Clinical Trial Randomized clinical trial (RCT) is the most effective way of conducting research on the efficacy and safety of newly developed drugs and medical treatment for public consumption. Like most experiments, there are usually two groups in conducting an RCT: the placebo group and experimental group. In the placebo group, the subjects receive a placebo drug or a drug that is already available and is used to treat a particular disease and in the treatment group, the subject receives the newly developed drug or treatment. However, in the RCT, the subjects that agreed to participate in the clinical trial are randomly assigned in either placebo or experimental group in order to eliminate observer bias and distribute the subjects’ variables evenly on all groups. Furthermore, RCT is either single-blinded or double-blinded. In single blinded RCT, the subjects cannot know if they are placed on placebo or experiment group. Moreover, the subject can not know anything about the progress of the trial. As for the double-blinded RCT, both the subject and the physician-scientists who are conducting the trial do not know which subject are in which group and whether a particular treatment’s progress. According to the Hellmans, because of the nature of RCT, physician-scientists are placed in a serious ethical bind that it poses to physician-scientists, therefore, we should abandon this practice altogether. In order to explain how this ethical dilemmaShow MoreRelatedEvaluation Of A Research Design1601 Words   |  7 Pagesstudies †¢ Numerous human characteristics are inherently not subject to experimental manipulation( e.g. blood type, personality, health beliefs, medical diagnosis) †¢ There are many variable that could technically be manipulated, but is forbidden on ethical grounds Disadvantages of nonexperimental research design: †¢ The result obtained and the relationship between the dependent and independent variable can never be absolutely clear and error free. †¢ Nonexperimental studies are conducted for comparativeRead MoreIs It The Right Decision For Withhold Experimental Drug Therapy?1763 Words   |  8 PagesDilemma: Was it the right decision to withhold experimental drug PLX4032 from Mr. Ryan for the sake of following protocol and not tainting the trial’s results, even though standard chemotherapy was ineffective? Assignment 4 (I need a title) The story of Thomas McLaughlin and Brandon Ryan is of a path that suddenly diverged with a roll of a dice. As cousins, not only did they share a life together by riding dirt bikes in the summer, spending holidays together at their grandmother’s house, and evenRead MoreAnalysis of an Ethical Dilemma1435 Words   |  6 PagesUnethical Marketing of Medical and Pharmaceutical Products-Part Two Tamara Floyd Sherome Graham Frances Kadambi Viviene Smith Grand Canyon University: NRS 437V Ethical Decision Making in Healthcare October 20th, 2013 Unethical Marketing of Medical and Pharmaceutical Products Part Two The pharmaceutical industry along with the manufacturers of healthcare products and technologies often encourage the misappropriation and distribution of marginally beneficial products and technologies in theRead MoreClinical Research Past and Present6962 Words   |  28 PagesClinical Research Past and Present Tina Ross-Cruz Abstract Research disasters have been noted for years. In the early years, the reasons for these disasters was that there were no regulations governing the protection of human beings; and there were no guidelines for safety and efficacy of a new medication or treatment prior to the use in humans. Now regulations and guidelines are in effect for the protection of human subjects. These guidelines and regulations also protect the researchersRead MoreClinical Trials Evaluation And Treatment Of Her2 Overexpressing Metastatic Breast Cancer3793 Words   |  16 PagesTanzir Mortuza PHAR 7100 Project 2 Clinical Trial Evaluation Primary Article: Vogel, Charles L., et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. Journal of Clinical Oncology 20.3 (2002): 719-726. 1.0 Introduction: Breast cancer is the most diagnosed cancer in the US for women (http://www.breastcancer.org/symptoms/understand_bc/statistics). Even though the diagnosis and treatment of this condition has improved dynamicallyRead More Alzheimers Disease and Research: Ethical Concerns Essay1904 Words   |  8 PagesCan patients with Alzheimer’s disease participate in clinical research? Theoretically, two radically opposite views regarding this issue can be posited. The first one, which is rather â€Å"conservative† could, in principle, argue that because of pervasive cognitive impairments AD patients are vulnerable and not capable of giving informed consent with a similar degree of responsibility as that of healthy individuals. When a surrogate’s decision is required for participation in research, this decisionRead MoreNurse Family Partnership : A Community Health Based Home Visiting Program1491 Words   |  6 Pagesand their mothers at home. This led to the creation of the p rogram which made use of nurses for home visitation purposes for first time low income mothers. He subsequently tested the program over the next three decades through the use of randomized clinical trials (RCTs) in Elmira, New York, in 1977; Memphis, Tennessee, in 1988; and Denver, Colorado, in 1994 with different populations; White, Black and Hispanic populations respectively. The use of RCT over the years helped to test effectiveness ofRead MoreThe Placebo Effect Succeeds As A Legitimate Treatment2395 Words   |  10 Pagesperfectly legal for a doctor to prescribe a placebo, however depending on the condition determines ethicality or not. Initially placebos were invented as an inert substance that was not supposed to be used in clinical medicine. Placebos have typically been tested in numerous clinical trials as a control group to austerely justify that a drug is modestly lucrative. Brain activity has been recorded in response to a placebo, showing some results of thrive. It has also been proven that placebo stimulatesRead MoreTranslational Research for Practice and Populations2952 Words   |  12 PagesConde-Agudelo, Belizan, J. Diaz-Rossello, J. (2014) Kangaroo Mother Care to Reduce Morbidity and Mortality in Low Birthweight Infants. Cochrane Neonatal Group. DOI: 10.1002/14651858.CD002771. Pub 2. | Evidence Strength2Evidence Hierarchy:Randomized Clinical Trial | Moore ER, Anderson GC, Bergman N, Dowswell T. Early skin-to-skin contact for mothers and their healthy newborn infants. Cochrane Database of Systematic Reviews 2012, Issue 5. Art. No.: CD003519. DOI: 10.1002/14651858.CD003519.pub3 | EvidenceRead MoreAnalytical Paper Evaluation : Heart Failure Essay1788 Words   |  8 PagesIntroduction†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.3 Importance†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...3 †¢ Affected individual†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..3 †¢ Members of the Family†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...4 †¢ Members of the Global Community†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...†¦.5 †¢ Ethical Considerations†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦5 Interrelationships†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..5 †¢ Nursing†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.5 †¢ Philosophy, Theory and Research†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦....6 †¢ Current Practice†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦....7 Reference

Monday, December 9, 2019

Mental Health and Depression Essay Example For Students

Mental Health and Depression Essay Human nutrition is the study of how food affects the health and survival of the human body. Human beings require food to grow, reproduce, and maintain good health. Without the food our bodies could not stay warm, build or repair tissues, and maintain a good heartbeat. Eating the right foods could help us rid certain diseases or recover faster other illness occur. These and other important functions are dueled by chemical substances in our food called nutrients. Nutrients p0lya a major role in maintaining the bodies organs in functioning at its proper level. The Basal Metabolism Rate (BMR) is in influenced by the body site and on state of nutrition. The BMR is an important diagnostic tool especially in determines disorders of the thyroid gland. Inadequate secretion of the thyroid may lead to greatly depresses metabolism with mental and physically lethargy. Depression is a complex illness with many facets of which mood is only one. Depression is a form of mental illness which a person experiences great sadness and despair in one. Depression can also be considered as self-destructive hatred, blaming oneself for being full of helpfulness. Depression can also be used to describe the blues a person may feel from time to time. Depressive disorders are at the present the highest-ranking problems in America. A variety of medical conditions can cause and lead to depression. A depressive disorder is a whole body illness involving your body, mood and thoughts. People with severe depressive disorder usually deal with a combination of genetics, behavioral, and environmental factors. People with these feelings have greater thoughts towards committing suicide. Fiftieth percent of depressed people commit and others attempt suicide. Most of these depressed persons suffer from malnutrition. Mental Health a, psychological state of well being, a sense of purpose in life. Self-esteem, self-assurance, and self-acceptance, are all characteristics of mental health. Mental health is term used to refer to the absense of mental disorder. Mental health is focused upon by a persons capability of dealing with strenous situations. Being able to elude cognitive, emotional, and dysfunctional behavior is good form of mental health. A positive strategy for the mental health and limiting depression is decreasing stresses. Sometimes there is much need for stress management. Psychological make-up also can be linked to depression. A number of different aspects of life can downside an individuals mental health. Depression is a major factor that affects a persons mental state. Many problems such as martial relationships, or financial difficulties in a persons life can lead to stress. Stresses can also onset depression. Stress management can be a positive factor in reducing the risk of depression. Depression is a common and costly mental illness that affects approximately 17.6 million Americans each year. Depression can affect a persons mental health. There are many different forms of depression that are linked to mental health disorders. A number of mental illnesses occur worldwide. The most common disorders are manic depression, schizophrenia, and severe depression. Manic depression is a bipolar disease that causes mood swings from manic to depression. Manic disorders affect a persons way of thinking and judgement Schizophrenia is an abnormal behavior, which distorts thought and perceptions from reality. Severe depression sometimes referred to as major depression enables a person to interact with daily situations. Major depression is manifested by a combination of symptoms that prohibit the ability to work, eat, and sleep. These episodes may reoccur numerous times throughout a persons life. Certain situations can drive a person into depressed state. Without proper treatment, symptoms of depression can last for weeks. A person must first have a physical and psychological evaluation to determine if in fact they do have a depressive disorder. .ub1cd0310cad083c38b7896f6e69deb13 , .ub1cd0310cad083c38b7896f6e69deb13 .postImageUrl , .ub1cd0310cad083c38b7896f6e69deb13 .centered-text-area { min-height: 80px; position: relative; } .ub1cd0310cad083c38b7896f6e69deb13 , .ub1cd0310cad083c38b7896f6e69deb13:hover , .ub1cd0310cad083c38b7896f6e69deb13:visited , .ub1cd0310cad083c38b7896f6e69deb13:active { border:0!important; } .ub1cd0310cad083c38b7896f6e69deb13 .clearfix:after { content: ""; display: table; clear: both; } .ub1cd0310cad083c38b7896f6e69deb13 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .ub1cd0310cad083c38b7896f6e69deb13:active , .ub1cd0310cad083c38b7896f6e69deb13:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .ub1cd0310cad083c38b7896f6e69deb13 .centered-text-area { width: 100%; position: relative ; } .ub1cd0310cad083c38b7896f6e69deb13 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .ub1cd0310cad083c38b7896f6e69deb13 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .ub1cd0310cad083c38b7896f6e69deb13 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .ub1cd0310cad083c38b7896f6e69deb13:hover .ctaButton { background-color: #34495E!important; } .ub1cd0310cad083c38b7896f6e69deb13 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .ub1cd0310cad083c38b7896f6e69deb13 .ub1cd0310cad083c38b7896f6e69deb13-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .ub1cd0310cad083c38b7896f6e69deb13:after { content: ""; display: block; clear: both; } READ: When looking at the life of one of history's greatest men, the lessons we might learn are countless, despite Irving Stone's fictional twists Essay Physicians have to first rule out all other possibilities before administering a medication. There must be a proper interview of the persons complete history. Lab test is also done to determine the symptoms the person is claiming to be having. Necessary treatment will depend on the outcome of the evaluation. Depression can be treated with antidepressant drugs. The human brain has neurotransmitters, which control our emotion and mood state. Antidepressants act on these neurotransmitters by altering the level of the depressed state. A depressed person will take .

Monday, December 2, 2019

Nirvana and the Red Hot Chili Peppers are just two Essays - Music

Nirvana and the Red Hot Chili Peppers are just two of the many popular bands from the nineties. People love them from all over the world. Although these two well-liked groups are similar, they are also different in many ways, such as in terms of active participation, genre of music, and performance. Each of these bands has a unique sound that draws people in to listen. Both their music are of the rock genre, but there are many different styles of rock. On the one hand, Nirvana's music is considered grunge rock, which is characterized by lazy vocals and loud guitar playing. On the other hand, the Red Hot Chili Peppers tend to give off a more alternative rock sound, which became popular around the time these two bands appeared. It is hard for groups to stick together through the years, but somehow the Red Hot Chili Peppers has managed to do it. The band still performs in concerts and goes on tours yearly. Unfortunately, Nirvana has been inactive since the tragic death of their lead singer and frontman, Kurt Cobain. Although Nirvana does not perform anymore, their music is still popular today. Experiencing a band's concert firsthand is an adrenaline rush. The loud music and flashing lights can be exciting. Fans describe the Red Hot Chili Peppers' performance as that accurately. They are very athletic on stage and tend to jump around. They are also very involved with the crowd. While Nirvana was a grunge band, they were calmer on stage and lackadaisical. It was as if they did not care, but the people still loved them. Although Nirvana and the Red Hot Chili Peppers are different, their differences do not set them apart from the same level of fame. Nirvana has broken up but is still just as famous as they were before the death of their lead singer. Their music has been covered by many artists, and their songs are instantly recognizable in many movie soundtracks. The Red Hot Chili Peppers still make music and perform in sold-out concerts all around the world giving their fans the music they want to hear.